The alliance between the Global Longevity Summit and the American Academy of Anti-Aging Medicine (A4M).) will take the form of a ground-breaking event to be held from 28 to 30 October 2025 at the Genolier Innovation Hub in Geneva. For three days, 300 international experts in longevity, regenerative medicine and applied biotechnology will meet in an intensive programme combining keynote lectures, expert panels, practical sessions and networking spaces designed to accelerate the translation of scientific knowledge into clinical practice.
The opening day will begin with Laurie Hofmann giving an overview of the current state of longevity science. Steven Horvath, creator of epigenetic clocks, will then present the keynote lecture on the molecular mechanisms of ageing and rejuvenation interventions. Gordan Lauc will then delve into the evolution of biological clocks and their role in predicting disease risk and evaluating anti-ageing therapies. The morning will continue with a panel of experts on epigenetics and biological biomarkers, followed by Dr Joe Purita's presentation on cellular senescence and rejuvenation therapies. The afternoon session will focus on technological innovations for longevity, precision medicine protocols applied to clinical practice and advanced diagnostic tools. The day will conclude with interactive SPARK sessions, aimed at transforming knowledge into action, and a welcome dinner to encourage networking among participants.
The second day will focus on applied areas of longevity, starting with Dr Melissa Sundermann's presentation on nutrition, fasting and metabolism as modulators of metabolic flexibility and long-term health. Dr Evelyn Bischoff will address advances in cognitive longevity and neurodegeneration, demonstrating strategies for reversing the "brain clock". Afterwards, a panel will bring together experts in stem cells, regenerative medicine and apheresis, exploring their role in reducing age-related pathologies. The morning programme will be rounded off with presentations by Dr Matt Kaeberlein on integrating longevity science into clinical practice and Dr Jennifer Pearlman on the impact of artificial intelligence and precision medicine in this field. Dr Hanwen Ou will present clinical applications of the Organic Acids Test as a tool for designing personalised strategies for metabolic ageing. After the lunch break, the afternoon block will be reserved for further SPARK sessions, reinforcing the interaction between science, clinical practice and real-world application.
The final day will open with Dr Andrea Maier's lecture on future directions in longevity research. She will be followed by Dr Jill Carnahan, who will address the role of immune modulation in the prevention and treatment of age-related chronic diseases, integrating strategies to optimise the resilience of the immune system. Dr. Aubrey de Grey, one of the most visionary leaders in biogerontology, will close the lecture series with a presentation on the limits, possibilities and ethical dilemmas of radical human life extension. The summit will conclude with a farewell lunch to round off three days of scientific reflection and strategic planning on the future of longevity medicine.
This programme reflects the joint mission of the Global Longevity Summit and A4M: to break down the barriers between laboratory and clinic, build bridges of collaboration and create a space where scientific innovations become applicable medical standards. With this, the event is positioned as an unmissable reference for those working at the frontier of life extension and human health.
Registration at this link: https://www.a4m.com/cart;cart,add_to_cart,2025_10_G_CH_GLS_DELEGATE,1.html
